The Simulation of strongly focused finite amplitude ultrasound and temperature field

نویسندگان

  • Chao Tao
  • Jing Mu
  • Gonghuan Du
چکیده

This paper simulates the temperature field generated by a high intensity focused ultrasound (HIFU) in a tissue-like material. The linear and nonlinear HIFU field are predicted respectively by solving the linear and nonlinear spherodial beam equations (SBE) using frequency domain method. And the temperature field is simulated by solving the “bioheat equation” with the finite-difference time-domain (FDTD) method. Because the spherodial beam equation can reliably applied to predict the HIFU field excited by a wider aperture angle transducer (for half-aperture angles of up to 40°), we simulate the heat pattern generated by the HIFU field with various half-aperture angles (10°, 20°, 30°, 40°). Numerical results reveal the nonlinearity of ultrasound field play crucial roles in the generation of temperature field. The peak temperature at focus predicted by a nonlinear equation field is evidently higher than that predicted by a linear equation especially when the aperture angle is wide because of the strongly absorption of the higher-frequency harmonics. The excess heat increases with the increase of the aperture angle and becomes significant large when the halfaperture angle is up to 40°.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A Numerical Investigation of the Time Reversal Mirror Technique for Trans-skull Brain Cancer Ultrasound Surgery

Introduction: The medical applications of ultrasound on human brain are highly limited by the phase and amplitude aberrations induced by the heterogeneities of the skull. However, it has been shown that time reversing coupled with amplitude compensation can overcome these aberrations. In this work, a model for 2D simulation of the time reversal mirror technique is proposed to study the possibil...

متن کامل

Numerical Study for Optimizing Parameters of High-Intensity Focused Ultrasound-Induced Thermal Field during Liver Tumor Ablation: HIFU Simulator

Introduction High intensity focused ultrasound (HIFU) is considered a noninvasive and effective technique for tumor ablation. Frequency and acoustic power are the most effective parameters for temperature distribution and the extent of tissue damage. The aim of this study was to optimize the operating transducer parameters such as frequency and input power in order to acquire suitable temperatu...

متن کامل

Blood Brain Barrier Disruption by Focused Ultrasound and Microbubbles: A Numerical Study on Mechanical Effects

Introduction: Microbubbles are widely used as contrast agent in diagnostic ultrasound. Recently they have shown good potential for applications in the therapeutic field such as drug delivery to the brain. Recent studies have shown focused ultrasound in conjunction with injected micro-bubbles could temporarily disrupt blood-brain barrier and let therapeutic agents transport into...

متن کامل

Transcranial Focused Ultrasound Modulates Electrical Behavior of the Neurons: Design and Implementation of a Model

Background: Recently, ultrasonic neuromodulation research has been an important and interesting issue. Ultrasonic neuromodulation is possible by the use of low-intensity transcranial focused ultrasound (tFUS) to stimulate or inhibit the neural structures. The primary capability of this method is the improvement in the treatment progress of certain neurological and psychiatric disorders noninvas...

متن کامل

Local Field Correction Effect on Dicluster Stopping Power in a Strongly Coupled Two-Dimensional Electron Gas System

We calculate the stopping power for heavy-ion diclusters moving in a strongly coupled two-dimensional electron gas system by using the local field corrected dielectric function at finite temperature. We obtain a parameterized local field correction factor based on a relation between the thermal compressibility and exchange-correlation energy in two-dimension. The interpolated parameter is deriv...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2004